| Course | Title | Units | Semester |
| 03-050 |
Study Abroad |
0 Units |
Fall |
| |
|
| 03-051 |
Study Abroad |
0 Units |
Spring |
| |
|
| 03-101 |
Biological Sciences First Year Seminars |
3 Units |
Fall and Spring Mini Session |
| Various seminars are offered that introduce first-year students to current topics of modern biology. These are mini courses that meet for half a semester. Topics have included: Proteins in Disease, Genes and Diseases, Pills and Poisons, Curing Cancer, Organ Transplantation and Blood Substitutes, and Prions-Mad Cows and Englishmen |
|
| 03-121 |
Modern Biology |
9 Units |
Fall and Spring |
| This is an introductory course that provides the basis for further studies in biochemistry, cell biology, genetics and molecular biology. This course emphasizes the chemical principles underlying biological processes and cell structures as well as the analysis of genetics and heredity from a molecular perspective. This is the introductory biology course for all science and non-science majors. |
|
| 03-122 |
Organismic Botany |
9 Units |
Spring |
| This course will provide an integrated overview of organismic botany, including historical perspectives. It surveys the organization of the plant kingdom above the cellular level, focusing particularly on the vascular plants, both fossil and extant. Emphasis is on major morphological, developmental and evolutionary patterns, and their interrelationships to the environment. On a sub-disciplinary basis, the course will include introductions to the basic principles of anatomy, morphology, ontogeny, speciation and macroevolution, phytogeography, ecology, and systematics. |
| Pre-req: 03-121 |
|
| 03-124 |
Modern Biology Laboratory |
9 Units |
Fall and Spring |
| This laboratory is designed to introduce students to modern concepts in the biological sciences. The experiments illustrate many of the principles covered in 03-121 and 03-130. |
| Pre-req: 03-121. Special permission required. |
|
| 03-125 |
Evolution and History of Life |
9 Units |
Intermittent |
| Historical emergence of evolutionary concepts. Recognition of evolutionary pattern (biological diversity in geological time); foundation theory of evolutionary process. Overview of modern understanding of the history of life. Relationships of the major existing domains, kingdoms of life, the past history of life and relationship to geological events. Early Earth; prebiotic evolution; origin of nucleic acids; the RNA world; endosymbiotic theory of the evolution of eukaryotes. Molecular nature of mutation. Overview of modern theory of evolutionary process. Microevolution, speciation (including concepts of species), and macroevolution, relationship of phylogenics and systematics. Molecular approaches to the study of evolution. Use of molecular methods in construction of phylogenies. Correlation of molecular studies with fossil record and morphological characters of extant and extinct forms. Evolutionary trends among major groups and organisms: A) Microbiological organisms. Eubacteria; archea; unicellular eukaryotes. B) Fungi. C) Plants. D) Animals. |
| Pre-req: 03-121 |
|
| 03-130 |
Biology of Organisms |
9 Units |
Spring |
| This course will survey the major organ systems in higher animals and humans, with an emphasis on cellular physiology and biochemistry. Current ideas of research and scientific controversy will also be presented. This course is intended to broaden students' exposure to biological systems. |
| Pre-req: 03-121 |
|
| 03-201 |
Undergraduate Colloquium for Sophomores |
1, 3 Units |
Fall |
| The purpose of this seminar series is to update biology undergraduates about university and departmental functions, seminars, etc. that are pertinent or useful. In addition, research talks by faculty and undergraduates will be used to introduce students to the research being conducted in faculty laboratories. Additional topics may include graduate and medical school applications, career options, topics in the press, and important scientific discoveries. |
|
| 03-202 |
Undergraduate Colloquium for Sophomores |
1, 3 Units |
Spring |
| |
|
| 03-210 |
Independent Study |
3 to 9 Units |
Fall and Spring |
| Students will read papers from the original literature under the direction of a faculty member. Students will be required to demonstrate mastery of the readings by discussions with the sponsoring faculty member, oral presentations, or writing of one or more papers summarizing and extending the information in the readings. If appropriate, students may write a program(s) to satisfy this last requirement.A student may take this course only once. |
| Pre-req: Special permission required |
|
| 03-211 |
Directed Reading |
9 Units |
All Semesters |
| Students will read papers from the primary research literature in an emerging research area. Recent topics have been human behavioral genetics and human diseases of the cytoskeleton. Emphasis is on classroom discussion, weekly written assignments, and a term paper. |
| Pre-req: Special permission required. |
|
| 03-231 |
Biochemistry I |
9 Units |
Fall |
| This course provides an introduction to molecules and processes found in living systems. Amino acids, sugars, lipids and nucleotides and their corresponding higher structures, the proteins, polysaccharides, membranes and nucleic acids are studied. Kinetics and mechanisms of enzymes as well as elementary metabolic cycles and the energetics of biological systems are discussed. |
| Pre-req: 03-121 |
| Co-req: 09-217 |
|
| 03-232 |
Biochemistry I |
9 Units |
Spring |
| This course provides an introduction to the application of biochemistry to biotechnology. The functional properties of amino acids, nucleotides, lipids, and sugars are presented. This is followed by a discussion of the structural and thermodynamic aspects of the organization of these molecules into higher-order structures, such as proteins, nucleic acids, and membranes. The kinetics and thermodynamics of protein-ligand interactions are discussed for non-cooperative, cooperative, and allosteric binding events. The use of mechanistic and kinetic information in enzyme characterization and drug discovery are discussed. Topics pertinent to biotechnology include: antibody production and use, energy production in biochemical systems, expression of recombinant proteins, and methods of protein purification and characterization. The course is an alternate to 03-231. |
| Co-req: 09-217 |
|
| 03-240 |
Cell Biology |
9 Units |
Spring |
| This course provides descriptive information and mechanistic detail concerning key cellular processes in six areas: membrane function, protein targeting, signaling, cytoskeleton, cell division, and cell interaction. An attempt is made to introduce the methodology that was used to obtain this information and to discuss how our understanding of these processes relates to the treatment of human disease. |
|
| 03-301 |
Undergraduate Colloquium for Juniors |
|
Fall |
| |
| Pre-req: 03-121 and (03-231 or 03-232) |
|
| 03-302 |
Undergraduate Colloquium for Juniors |
1, 3 Units |
Spring |
| |
|
| 03-310 |
Introduction to Computational Biology |
9 Units |
Spring |
| This course covers the application of computers to solve problems in interested students from other departments. It is intended for students without computer programming experience (students with a desire to apply programming methods to these problems should take the more advanced course 03-510, Computational Biology). Topics covered are computational molecular biology (analysis of protein and nucleic acid sequences), biological modeling and simulation (including computer models of neuron behavior, biochemical kinetics, and simulation of mutation), and biological imaging. Course work consists primarily of homework assignments making use of software packages for these applications. |
| Pre-req: 03-121, 21-118, and 99-101 |
|
| 03-311 |
Introduction to Computational Molecular Biology |
6 Units |
Spring |
| This course presents both the theoretical underpinnings of computational methods used in modern molecular biology and practical training in use of these methods. It is intended for students without computer programming experience. Topics included are accessing Internet molecular biology resources, restriction enzyme analysis, finding protein coding regions (open reading frames), sequence alignment, homology searching, finding sequence features (e.g., promoters), and elementary protein structure prediction. Course work consists primarily of homework assignments making use of software packages for these applications. Students may use only one of the following for credit, 03-310, 03-311, or 03-510. |
| Pre-req: 03-131, 99-101 or equivalents. |
|
| 03-315 |
Magnetic Resonance Imaging in Neuroscience |
9 Units |
Spring |
| The course is designed to introduce students to the fundamental principles of magnetic resonance imaging (MRI) and its application in neuroscience. MRI is emerging as the preeminent method to obtain structural and functional information about the living human brain. This methodology has helped to revolutionize neuroscience and the study of human cognition. The specific topics covered in this course will include: introduction to spin gymnastics, survey of imaging methods, structural brain mapping, functional MRI (fMRI), and MR spectroscopy (MRS). Approximately, one third of the course will be devoted to introductory concepts of magnetic resonance, another third to the discussion of MRI methods, and the remaining third will cover a broad range of neuroscience applications. Guest lectures will be incorporated into the course from neuroscientists and psychologists who use MRI in their own research. |
| Pre-req: 03-121 and 21-117 or permission of instructor |
|
| 03-330 |
Genetics |
9 Units |
Fall |
| The mechanisms of transmission of inherited traits in viruses, bacteria, fungi, plants and animals are discussed. Molecular mechanisms of gene expression and gene regulation are analyzed. Recombinant DNA and cloning of genes and their uses and applications in genetic analysis, biotechnology, forensics, agriculture, medicine, and the pharmaceutical industry are presented. The coding capacity, genes and genomes of diverse organisms for which total DNA sequence information is available are considered. A special topic in human genetics is considered yearly; recent examples are the genetics of cancer, hypercholesterolemia, and human behavioral genetics. |
| Pre-req: (03-231 or 03-232) and 03-240 |
|
| 03-343 |
Experimental Techniques in Molecular Biology |
12 Units |
Fall |
| This laboratory course is designed to teach experimental methods of modern biology. Experiments in microbial genetics and physiology, molecular biology and eukaryotic genetics are performed. This course is designed to be taken during the junior year and is intended to prepare students for undergraduate research. |
| Pre-req: (03-231 or 03-232) and 09-222 |
| Co-req: 03-330 |
|
| 03-344 |
Experimental Biochemistry |
12 Units |
Spring |
| This course is designed to be taken as a sequel to 03-343. Experiments cover a variety of methods for investigating the structure and function of biological molecules. Experimental methods with proteins, enzyme kinetics, carbohydrates, lipids, and isolation and quantitation of biological molecules are covered. During the last five weeks students plan and carry out an original research project. |
| Pre-req: (03-231 or 03-232) and 03-343 |
|
| 03-345 |
Experimental Cell and Developmental Biology |
12 Units |
Spring |
| This laboratory is designed to teach concepts and experimental methods in cell and developmental biology. Students work with a variety of organisms to examine how cells traverse development - from rapidly dividing, undifferentiated cells, through cell commitment and the establishment of spatial and temporal patterns of gene expression, to the specific characteristics and responses of terminally differentiated cells. The course makes extensive use of video microscopy with phase contrast, DIC and fluorescence microscopes. Biochemical, immunological and molecular biological techniques are used to probe the molecules and processes of cells undergoing development. |
| Pre-req: (03-231 or 03-232) and 03-240 and 03-330 and 03-343 |
|
| 03-350 |
Developmental Biology |
9 Units |
Spring |
| Developmental biology is the study of how organisms arise from a single cell the fertilized egg. The molecular pathways that control development also underlie many human diseases. This course focuses on fundamental processes that are common to the development of multicellular animals and explores the experimental and conceptual paradigms that have been used to study these processes. It provides an overview of our current knowledge of the cellular and molecular mechanisms that underlie development. |
| Pre-req: (03-231 or 03-232) and 03-240 and 03-330 |
|
| 03-360 |
The Biology of the Brain |
9 Units |
Fall |
| This course will survey a range of topics found in the science of neurobiology. Neurobiology is the study of the nervous system, its development, its function and its diseases. Topics will include Evolution and Development of the Nervous System, Electrophysiology of Neurons, Human Neuroanatomy, Anatomy and Functioning of the Sensory Systems and Molecular Genetics of the Nervous System. The focus of the course is on how a scientist discovers the inner workings of the brain. A vast array of living organisms have brains. Science has shown that the study of "simple" brains can tell us a great deal about how all brains function, including human brains. As such, in this class, we will study aspects of the neurobiology of many different organisms. |
| Pre-req: (03-231 or 03-232) |
| Co-req: 03-330 |
|
| 03-380 |
Virology |
9 Units |
Fall |
| The concepts and methods of virology are studied with emphasis on animal viruses. A variety of DNA and RNA viruses, including some new and emergent viruses, are discussed within the framework of genetics, molecular biology, cell biology, immunology and epidemiology. Viral and cellular oncogenes and the processes of oncogenic transformation will be examined. A discussion of prions will also be included. These are novel, proteinaceons, infectious agents which, unlike viruses lack nucleic acids. |
| Pre-req: 03-240 |
| Co-req: 03-330 |
|
| 03-401 |
Undergraduate Colloquium for Seniors |
1, 3 Units |
Fall |
| |
|
| 03-402 |
Undergraduate Colloquium for Seniors |
1, 3 Units |
Spring |
| |
|
| 03-410 |
Independent Study Biological Study |
3 to 9 Units |
Fall and Spring |
| |
|
| 03-411 |
Topics in Research |
1 Units |
Fall and Spring |
| During the year students attend and submit brief summaries of weekly seminars given by outside speakers or members of the Biology Department on current research topics in modern biology; some seminars outside of the department may be substituted. |
|
| 03-412 |
Topics in Research |
1 Units |
Spring |
| During the year students attend and submit brief summaries of weekly seminars given by outside speakers or members of the Biology Department on current research topics in modern biology. Some seminars outside of the department may be substituted. |
|
| 03-438 |
Physical Biochemistry |
9 Units |
Fall |
| The physical properties of biological macromolecules and the methods used to analyze their structure and function are discussed. Topics covered include: protein architecture and folding; nucleic acid structures and energetics; structure determination by X-ray crystallography and NMR; biological spectroscopy with emphasis on the biological applications of absorption, fluorescence, NMR, IR and CD spectroscopies; the kinetics and thermodynamics of protein-ligand interactions; enzyme catalysis; and the use of hydrodynamics and electrophoresis in the characterization of biological macromolecules. One or two research topics selected from the current literature are examined in depth as in-class case studies. |
| Pre-req: (03-231 or 03-232) and 33-112 and 09-214. |
|
| 03-439 |
Introduction to Biophysics |
9 Units |
Fall |
| This course develops the use of physical methods in the study of biological systems. The forces that play roles in biological systems and the role of thermal energy are introduced. These concepts are used to elucidate protein and membrane structure and function. Topics discussed include x-ray diffraction, protein structure, helix-coil transitions, double layer potentials, membrane structure and transport, Nernst-Planck equations and electrochemical potential, action potentials and voltage sensitive channels. The treatment of biophysical phenomena and methods is based on physical principles, which will be treated with appropriate mathematics when necessary. |
| Pre-req: 03-121 and 09-105 and 33-111 and 33-112 |
|
| 03-441 |
The Molecular Biology of Prokaryotes |
9 Units |
Spring |
| The course covers the molecular biology and genetic analysis of prokaryotic microorganisms with particular attention to certain selected topics. Among the topics covered are: the transcriptional and translational regulation of gene expression at the molecular level in Escherichia coli and Salmonella typhimurium, the structure and function of flagella, the molecular mechanisms of bacterial chemotaxis and motility, and the principles of self-assembly and catalyzed assembly of virus particles. |
| Pre-req: (03-231 or 03-232) and 03-33003-330 |
|
| 03-442 |
Molecular Biology Of Eukaryotes |
9 Units |
Fall |
| The structure and expression of eukaryotic genes are discussed, focusing on model systems from a variety of organisms including yeast, Drosophila and humans. Topics discussed include (1) control of gene expression at the level of transcription, pre-mRNA splicing and translation, (2) chromosome structure, including origins of replication, centromeres, telomeres, transposons, and regulated chromosomal rearrangements, and (3) recombination, mutations and repair. |
| Pre-req: 03-441 |
|
| 03-445 |
Undergraduate Research |
1 to 18 Units |
Fall and Spring |
| Students may investigate research problems under the supervision of members of the faculty. |
| Pre-req: Permission of a research faculty advisor required. |
|
| 03-510 |
Computational Biology |
12 Units |
Spring |
| This course covers a range of applications of computers to solve problems in biology and medicine. Specific topics covered are computational molecular biology (analysis of protein and nucleic acid sequences), biological modeling and simulation (including computer models of neuron behavior, biochemical kinetics, and simulation of mutation), and biological imaging. Course work will include use of software packages for these applications, reading of scientific papers, and programming assignments. |
| Pre-req: 03-121 and 15-211 or permission of instructor |
|
| 03-511 |
Computational Genomics and Molecular Biology |
9 Units |
Fall |
| This course is intended to be a second course in computational molecular biology, following 03-510. The first half of the course will begin with a review of pairwise sequence alignment and dynamic programming and then focus on problems in multiple sequence alignment and phylogeny reconstruction. The material in the second half of the course will be drawn from recent results in computational genomics and will also cover computational molecular biology algorithms in depth. |
| Pre-req: 03-510 or permission of instructor |
|
| 03-534 |
Biological Imaging and Fluorescence Spectroscopy |
9 Units |
Fall |
| This course covers principles and applications of optical methods in the study of structure and function in biological systems. Topics to be covered include: absorption and fluorescence spectroscopy; interaction of light with biological molecules, cells, and systems; design of fluorescent probes and optical biosensor molecules; genetically expressible optical probes; photochemistry; optics and image formation; transmitted-light and fluorescence microscope systems; laser-based systems; scanning microscopes; electronic detectors and cameras: image processing; multi-mode imaging systems; microscopy of living cells; and the optical detection of membrane potential, molecular assembly, transcription, enzyme activity, and the action of molecular motors. This course is particularly aimed at students in science and engineering interested in gaining in-depth knowledge of modern light microscopy. |
| Pre-req: (03-231 or 03-232) and 03-240 and 09-218 and 09-214. |
|
| 03-545 |
Honors Research |
9 Units |
Fall and Spring |
| This semester of research consists primarily of research and preparation of an acceptable written thesis. Oral presentation and defense of the thesis research will be required. This course ordinarily will be taken in the second semester of the senior year. Permission of the research advisor required. |
| Pre-req: 03-330 |
|
| 03-550 |
Developmental Genetics |
9 Units |
Fall |
| This course will examine in detail the genetic basis of specific developmental processes and the use of genetic methods to investigate general problems in developmental biology. Lectures and readings will focus primarily on studies using Drosophila melanogaster, Caenorhabditis elegans, zebrafish, and the laboratory mouse. Consideration will be given to both the identification and the functional dissection of genes involved in a variety of developmental processes ranging from the establishment of embryonic polarity to the control of cell proliferation. Questions concerning the evolutionary continuity of developmental regulatory mechanisms and the links between different developmental processes will also be explored. |
| Pre-req: 03-330 |
|
| 03-620 |
Techniques in Electron Microscopy |
9 Units |
Spring |
| This course is designed to teach basic methods in transmission electron microscopy to graduate and undergraduate students. Sophomores with an interest in electron microscopy are encouraged to enroll, and will have the option and opportunity to utilize their skills in various laboratories during their junior or senior year. The course will be offered once each year, during the Spring semester. Course enrollment will be limited to 4-6 students. Preferential enrollment will be given to graduate students and undergraduate students who have demonstrated a need for this technique in their research. The class will include one hour of lecture and 4 hours of laboratory each week (some additional laboratory time outside of the scheduled laboratory time is required). Students will learn basic methods in specimen preparation for both transmission and scanning electron microscopy (fixation, embedding and ultramicrotomy, drying and metal coating) and will be trained in the operation of both the Hitachi 7100 and 2460N electron microscopes. Lectures and laboratories during the last few weeks of the semester will introduce the students to special techniques (e.g. immunoelectron microscopy , cryoultramicrotomy, freeze substitution, variable pressure SEM, etc.) and will allow them to work with samples from their own research. |
|
| 03-700 |
MS Thesis Research |
3 to 36 Units |
All Semesters |
| An independent investigation on a project selected from a major area of research study with the advice and approval of the faculty advisor. Required of students enrolled in the Master of Science program. |
|
| 03-711 |
Computational Genomics and Molecular Biology |
9 Units |
Fall |
| The proposed course is intended to be a second course in computational molecular biology, following 03-510. The first half of the proposed course will begin with a review of pairwise sequence alignment and dynamic programming and then focus on problems in multiple sequence alignment and phylogeny reconstruction. The material in the second half of the course will be drawn from recent results in computational genomics. Multiple sequence alignment and phylogeny reconstruction will be covered in the proposed course. The course will cover computational molecular biology algorithms in depth and will focus on problems in genomics. |
| Pre-req: 03-510 or permission of instructor |
|
| 03-730 |
Advanced Genetics |
9 Units |
Spring |
| This course considers selected current topics in genetics at an advanced level. Emphasis is on classroom discussion of research papers. Topics change yearly. Recent topics have included nucleocytoplasmic trafficking of RNA in yeast, genome imprinting in mammals, chromatin boundaries, and long distance gene regulation in Drosophila. |
| Pre-req: 03-441 and (03-422 or 03-742) |
|
| 03-738 |
Physical Biochemistry |
9 Units |
Fall |
| The physical properties of biological macromolecules and the methods used to analyze their structure and function are discussed. Topics covered include: protein architecture and folding; nucleic acid structures and energetics; structure determination by X-ray crystallography and NMR; biological spectroscopy with emphasis on the biological applications of absorption, fluorescence, NMR, IR and CD spectroscopies; the kinetics and thermodynamics of protein-ligand interactions; enzyme catalysis; and the use of hydrodynamics and electrophoresis in the characterization of biological macromolecules. One or two research topics selected from the current literature are examined in depth as in-class case studies. |
| Pre-req: (03-231 or 03-232) and 33-112 and 09-214. |
|
| 03-741 |
Advanced Cell Biology |
9 Units |
Spring |
| This course covers fourteen topics in which significant recent advances or controversies have been reported. For each topic there is a background lecture by the instructor, student presentations of the relevant primary research articles and a general class discussion. Example topics are: extracellular matrix control of normal and cancer cell cycles, force generating mechanisms in transmembrane protein translocation, signal transduction control of cell motility, and a molecular mechanism for membrane fusion. |
| Pre-req: (03-231 or 03-232) and 03-240 |
|
| 03-742 |
Molecular Biology Of Eukaryotes |
9 Units |
Fall |
| The structure and expression of eukaryotic genes are discussed, focusing on model systems from a variety of organisms including yeast, Drosophila and humans. Topics discussed include (1) control of gene expression at the level of transcription, pre-mRNA splicing and translation, (2) chromosome structure, including origins of replication, centromeres, telomeres, transposons, and regulated chromosomal rearrangements, and (3) recombination, mutations and repair. |
| Pre-req: 03-441 |
|
| 03-751 |
Advanced Developmental Biology |
9 Units |
Fall |
| This course examines current topics in developmental biology at an advanced level. The course is team-taught by faculty from Carnegie Mellon University, the University of Pittsburgh Department of Biological Sciences, and the University of Pittsburgh Medical School. Each year several areas of current research are examined. Previous topics have included pattern formation, molecular signaling pathways, morphogen gradients, cell movements, and stem cells. Emphasis is on critical reading of original research papers and classroom discussion, with supporting lectures by faculty. |
| Pre-req: 03-350 |
|
| Course | Title | Units | Semester |
|
| 06-100 |
Introduction to Chemical Engineering |
12 Units |
Fall and Spring |
| We equip students with creative engineering problem-solving techniques and fundamental chemical engineering material balance skills. Lectures, laboratory experiments, and recitation sessions are designed to provide coordinated training and experience in data analysis, material property estimation for single- and multi-phase systems, basic process flowsheeting, reactive and non-reactive mass balances, problem solving strategies and tools, and team dynamics. The course is targeted for CIT First Year students. |
| Co-req: 09-105, 21-115, 21-116 |
|
| 06-200 |
Sophomore Research Project |
variable Units |
Fall and Spring |
| Research projects under the direction of the Chemical Engineering faculty. The nature of the project, the number of, and the criteria for grading are to be determined between the student and the faculty supervisor. The agreement should then be summarized in a one-page project description for review by the faculty advisor. A final written report or an oral presentation of the results is required. |
|
| 06-221 |
Thermodynamics |
9 Units |
Fall |
| This course introduces students to the process thermodynamics of single component systems. Topics include equilibrium and thermodynamic state variables; heat and work; conservation of energy and the first law of thermodynamics; entropy balances and the second law of thermodynamics; reversibility; free energies; interconversion of heat and work via engines, refrigeration and power cycles; absolute temperature and the third law of thermodynamics; equations of state; principle of corresponding states; thermodynamic property relationships; changes of state; phase equilibrium and stability in single component systems; vapor pressure and phase transition. |
|
| 06-222 |
Sophomore Chemical Engineering Seminar |
1 Units |
Fall |
| This course provides an overview of the chemical engineering profession. It discusses the rationale for the curriculum, career paths, resume writing, written communication skills, and ethics, and also involves a project on the use and manufacture of chemicals. |
|
| 06-261 |
Fluid Mechanics |
9 Units |
Spring |
| The principles of fluid mechanics as applied to engineering, including unit operations, are discussed; examples include flow in conduits, process equipment, and commercial pipes, flow around submerged objects, and flow measurement. Microscopic mass and momentum balances are described, including the continuity and Navier-Stokes equations, and modern solution techniques will be explored. Microscopic flow structures will be determined for flow visualization. Boundary layer theory, turbulence, and non-Newtonian fluids are also discussed. A case-study project based on new technological advancements and environmental engineering is also required. |
| Pre-req: 21-259 |
| Co-req: 06-262, 06-100 |
|
| 06-262 |
Mathematical Methods of Chemical Engineering |
12 Units |
Spring |
| Mathematical techniques are presented as tools for modeling and solving engineering problems. Modeling of steady-state mass and energy balance problems using linear and matrix algebra, including Gaussian elimination, decomposition, and iterative techniques. Modeling of unsteady-state engineering problems using linear and nonlinear differential equations. Analytical techniques, including Laplace transforms, and numerical techniques for the solution of first-and higher-order differential equations and systems of differential equations arising in engineering models. Finally, the modeling of processes affected by chance and subject to experimental error; statistical and regression techniques within the context of experimental design and data analysis. |
| Pre-req: 06-221 and 21-118 |
|
| 06-300 |
Junior Research Project |
variable Units |
Fall and Spring |
| Research projects under the direction of the Chemical Engineering faculty. The nature of the project, the number of, and the criteria for grading are to be determined between the student and the faculty supervisor. The agreement should then be summarized in a one-page project description for review by the faculty advisor. A final written report or an oral presentation of the results is required. |
|
| 06-321 |
Chemical Engineering Thermodynamics |
9 Units |
Fall |
| The objective of this course is to cover principles and solution techniques for phase and chemical equilibria in multicomponent systems. Topics include thermodynamic properties of ideal and non-ideal mixtures; criteria for equilibrium; chemical potential, fugacity and activity coefficients; flash calculations; Gibbs energy minimization; thermodynamics of chemical reactions including equilibrium conversions. |
| Pre-req: 06-221 |
|
| 06-322 |
Junior Chemical Engineering Seminar |
2 Units |
Fall |
| This course discusses career choices for chemical engineers, professional practice, including alternate career paths, global industry, and graduate studies. It also emphasizes writing, interview skills and oral presentations. Safety, environmental and ethical issues are illustrated in projects and via invited lectures. |
|
| 06-323 |
Heat and Mass Transfer |
9 Units |
Fall |
| This course presents the fundamentals of heat and mass transfer, including steady-state and unsteady-state heat conduction and molecular diffusion, convection, and thermal radiation, with application to heat and mass transfer processes. Development of dimensionless quantities for engineering analysis is emphasized. |
| Pre-req: 06-262 or 21-260 |
|
| 06-361 |
Unit Operations of Chemical Engineering |
9 Units |
Spring |
| This course comprises many of the standard operations in chemical plants such as gas absorption, heat exchange, distillation and extraction. The design and operation of these devices is emphasized. A project dealing with a novel unit operation is also investigated. |
| Pre-req: 06-321 and 06-323 |
|
| 06-362 |
Chemical Engineering Process Control |
6 Units |
Spring |
| This course presents basic concepts of process dynamics and feedback control. Included are selection of measurements and manipulated variables, definition of transfer functions, creation of block diagrams and closed loop configurations. The course also covers concepts of open loop and closed loop stability, and tuning of PID controllers. |
| Pre-req: 06-262 |
|
| 06-363 |
Transport Process Lab |
6 Units |
Spring |
| Develop skills for proposing, designing, planning, implementing, interpreting, and communicating the results of experiments in fluid flow and heat and mass transfer. Oral and written reports are required. |
| Pre-req: 06-261 and 06-323 |
|
| 06-400 |
Senior Research Project |
variable Units |
Fall and Spring |
| Research projects under the direction of the Chemical Engineering faculty. The nature of the project, the number of, and the criteria for grading are to be determined between the student and the faculty supervisor. The agreement should then be summarized in a one-page project description for review by the faculty advisor. A final written report or an oral presentation of the results is required. |
|
| 06-421 |
Chemical Process Systems Design |
12 Units |
Fall |
| Screening of processing alternatives. Computational strategies for preliminary material and energy balances in large chemical processes. Preliminary sizing of process equipment. Cost estimation and evaluation for chemical plants. Strategies for synthesizing energy networks and separation sequences. Preliminary design of a large industrial project. |
| Pre-req: 06-321 |
| Co-req: 06-422 |
|
| 06-422 |
Chemical Reaction Engineering |
9 Units |
Fall |
| Fundamental concepts in the kinetic modeling of chemical reactions, the treatment and analysis of rate data. Multiple reactions and reaction mechanisms. Analysis and design of ideal and non-ideal reactor systems. Energy effects and mass transfer in reactor systems. Introductory principles in heterogeneous catalysis. |
| Pre-req: 09-347 |
|
| 06-423 |
Unit Operations Lab |
9 Units |
Fall |
| A series of open-ended laboratory projects illustrate the principles of unit operations and process control. Experiments are designed to be relevant to current industrial, environmental, and safety practices. Examples include distilling mixtures, such as ethanol and water; removing pollutants from stack gasses; controlling pH in tank systems with flow; testing mixture explosion properties; operating liquid-liquid extraction systems, such as ethanol and water; designing reactors based on the reaction kinetics of ethane hydrogenolysis; and separating oxygen and nitrogen in air using a hollow-fiber membrane. Oral and written reports are required. |
|
| 06-426 |
Experimental Colloid Surface Science |
9 Units |
Fall |
| Laboratory exercises will deal with preparation and stabilization of colloids, flocculation, micellar aggregates, surface tension, contact angle, spreading and adsorption. Basic concepts will be related to practical problems of wetting, lubrication, foaming, adhesion, coatings and corrosion. |
| Co-req: 06-607, 09-221 |
|
| 06-461 |
Process Design Project |
6 Units |
| Computer-aided design of a large industrial project involving synthesis of process, energy and material balances and economic evaluation. Extensive report on the project must be submitted. |
| Pre-req: 06-421 |
|
| 06-462 |
Economics and Optimization |
6 Units |
| Formulation and solution of mathematical optimization problems with and without constraints. Objective functions are based on economics or functional specifications. Both discrete and continuous variables are considered. |
| Co-req: 06-461 |
|
| 06-466 |
Experimental Polymer Science |
9 Units |
Spring |
| Macromolecular behavior in bulk and in solution will be explored in experiments on tensile strength, elasticity, swelling of networks, solution viscosity, melt flow, and polymerization reactions. Particular reference will be made to aspects affecting production and fabrication of polymeric materials. |
| Pre-req: 09-221 and (06-609 or 09-509) |
|
| 06-606 |
Computational Methods for Large Scale Process Design & Analysis |
9 Units |
Spring |
| This course deals with the underlying computer-aided design techniques for steady-state and dynamic simulation, numerical solution and decomposition strategies for large systems of sparse nonlinear algebraic equations, stiff ordinary differential equations, strategies for mixed algebraic/differential systems and computer architectures for flowsheeting systems. |
| Pre-req: 06-262 and 06-202 |
|
| 06-607 |
Physical Chemistry of Colloids and Surfaces |
9 Units |
Spring |
| Thermodynamics of surfaces; adsorption at gas, liquid, and solid interfaces; capillarity; wetting, spreading, lubrication and adhesion; properties of monolayers and thin films; preparation and characterization of colloids; colloidal stability, flocculation kinetics, micelles, electrokinetic phenomena and emulsions. |
| Pre-req: 06-221 and 09-347 |
|
| 06-608 |
Safety Issues in Science and Engineering Practice |
3 Units |
Fall |
| This course will expose students to personal safety issues encountered in normal science and engineering practice. Topics to be discussed include mechanical, electrical, chemical, radiation, and biological hazards to provide an awareness of these hazards and to inform students of appropriate action to be taken in the event of accidents. |
|
| 06-609 |
Physical Chemistry of Macromolecules |
9 Units |
Fall |
| This course develops fundamental principles of polymer science. Emphasis is placed on physio-chemical concepts associated with the macromolecular nature of polymeric materials. Engineering aspects of the physical, mechanical and chemical properties of these materials are discussed in relation to chain microstructure. Topics include an introduction to polymer science and a general discussion of commercially important polymers; Molecular weight; condensation and addition synthesis mechanisms with emphasis on molecular weight distribution; solution thermodynamics and molecular conformation; rubber elasticity; and the rheological and mechanical properties of polymeric systems. |
|
| 06-610 |
Rheology and Structure of Complex Fluids |
9 Units |
Fall |
| This course will cover the basic concepts of rheology and mechanical behavior of fluid systems. Both the experimental and theoretical aspects of rheology will be discussed. The basic forces influencing complex fluid rheology and rheology will be outlined and discussed; including excluded volume, van der Waals, electrostatic and other interactions. Methods of characterizing structure will be covered including scattering techniques, optical polarimetry and microscopy. Examples will focus on several types of complex fluids including polymer solutions and melts, gelling systems, suspensions and self-assembling fluids. |
| Pre-req: 06-609 or 09-509 |
|
| 06-619 |
Semiconductor Processing Technology |
9 Units |
Spring |
| This is an introductory course to the physical and chemical concepts involved in integrated circuit (IC) processing. The material focuses on basic principles in chemical reaction engineering and their application to IC process engineering. Topics include elementary theory of semiconductor devices; adsorption and reaction on semiconductor surfaces; process principles in crystal growth, diffusion, oxidation, and vapor deposition. |
| Pre-req: 06-422 and 09-347 |
|
| 06-620 |
Special Topics in Atmospheric Chemistry |
9 Units |
Spring |
| This course will explore global atmospheric chemistry through a series of case studies: Stratospheric Ozone, Global Methane and OH, and Urban and Regional Ozone. Each case will begin with a description of the chemistry and atmospheric physics fundamental to the particular problem. Students will formulate testable mathematical models incorporating that chemistry and physics, turning then to existing atmospheric data sets to test current understanding. The emphasis of this course is to develop an understanding of how to pose a testable hypotheses in a complex chemical environment such as the atmosphere, validate or refute those hypotheses, and then by extension predict how the system will respond to perturbations. A particular objective is to explore how to extend this methodology from the stratosphere and background troposphere (the first two cases), where it has been applied with success, to the much more complicated problem of urban and regional air quality. |
|
| 06-621 |
Biotechnology and Environmental Processes |
9 Units |
Fall |
| This course has two sections. The first section covers microbial physiology and metabolism, fermentation and respiration, metabolic regulation, bioconversions, recombinant DNA methodology and gene cloning. The second section covers separation and purification, kinetics and design of biological reactors, mass transfer limitations within cell suspensions, and control of fermentation processes. |
|
| 06-622 |
Bioprocess Design |
9 Units |
Fall |
| This course is designed to link concepts of cell culture, bioseparations, formulation and delivery together for the commercial production and use of biologically-based pharmaceuticals; products considered include proteins, nucleic acids, and fermentation-derived fine chemicals. Associated regulatory issues and biotech industry case studies are also included. The format of the course is a mixture of equal parts lecture, open discussion and participant presentation. Course work consists of team-oriented problem sets of an open-ended nature and individual-oriented industry case studies. The goals of the course work are to build an integrated, technical knowledge base of the manufacture of biologically based pharmaceuticals and the US biotechnology industry. A fair knowledge of cell culture and fermentation operations is desirable. |
|
| 06-630 |
Atmospheric Chemistry, Air Pollution and Global Change |
12 Units |
Fall |
| Principles necessary to understand the atmospheric behavior of air pollutants on urban, regional, and global scales. Key topics include atmospheric gas-, aqueous-, and aerosol-phase chemistry; removal processes and residence times; aerosol physics; pollutant effects on visibility and the energy balance of the planet; mathematical modeling of air pollution. The student completing this course will understand the fundamentals of atmospheric chemistry and physics and their relationship to urban, regional, and global pollution problems. |
|
| 06-640 |
Principles and Applications of Molecular Simulation |
9 Units |
Spring |
| This course will introdu ce modern concepts and methods for simulating physical and thermodynamics properties of materials from atomic-scales, with special emphasis on the gas and liquid states. Strengths and limitations of molecular simulation methods will be discussed, topics will include basic statistical mechanics, interatomic potentials, Molecular Dynamics methods, Monte Carlo methods, computation of phase coexistence curves, and Brownian Dynamics. |
| Pre-req: 06-262 and 06-321 |
|
| Course | Title | Units | Semester |
|
| 09-101 |
Introduction to Experimental Chemistry |
3 Units |
Fall and Spring |
| This is a seven session chemistry laboratory course that is designed to introduce students to some basic laboratory skills, techniques, and equipment commonly used in experimental scientific investigations. Experiments include: (1) An organic synthesis (the preparation and purification of aspirin), (2) Quantitative determination of aspirin by a Beer's Law analysis and a chromatographic (TLC) analysis of the ingredients in nonprescription medications, (3) Kinetics (determining the order and reaction rate constant for a reaction) , (4) An acid-base titration analysis (including the identification of an unknown organic acid), (5) Transition Metal Complexes (synthesis and color study of a coordination compound and a thermochemical study of a ligand replacement reaction of transition metal complexes using a temperature data acquisition/analysis device; Labworks II or CBL, (6) Polymers (determining the molecular weight of a polymer by an end-group analysis), and (7) Biochemistry (total iron content, iron release properties, and structure of ferritin, the iron storage protein). 1 hr. lec., 3 hrs. lab. |
|
| 09-102 |
First Year Chemistry Seminar |
3 Units |
Fall and Spring Mini Session |
| A selection of mini-courses offered to introduce first-year students to special topics in modern chemistry. The courses meet for half a semester and may include some hands-on laboratory and computer experiences. Topics vary, but have included: Chemistry of the Environment, Macromolecules for Nanotechnology, Polymers and the Modern World, Kaboom and Other Approaches to Teaching Science, Dating Using Radioactivity and Computer Molecular Modeling. Enrollment limited to first-year MCS students. |
|
| 09-103 |
Atoms, Molecules and Chemical Change |
9 Units |
Fall |
| This is a one-semester introductory college level course designed for non-science majors who have had a high school course in chemistry. Objectives are to provide students with an understanding of basic chemical principles and to show how these are applied in so many different and practical applications, from air-bags to the cancer treatment material cis-platinum. Major topics include: measurements, matter, atomic theory and the Periodic Table, chemical bonding, stoichiometry and chemical reactions, properties of aqueous solutions, states of matter (solids, liquids and gases), and acid-base chemistry. Additional topics include: chemical equilibrium, thermochemistry, reaction rates, and nuclear chemistry. Students should gain confidence in applying scientific reasoning concepts to situations beyond the course. 3 hrs. lec., 1 hr. rec. |
|
| 09-104 |
Fundamental Aspects of Organic Chemistry and Biochemistry |
9 Units |
Spring |
| This course is designed to follow 09-103 for non-science majors although it is possible for students with a good high school chemistry course to enter directly into 09-104. The course covers the structure, nomenclature and properties of organic molecules at a depth required to understand the function of lipids, carbohydrates, proteins and nucleic acids. Considerable emphasis is given to an understanding of stereoisomerism and its importance in biochemical processes. The relation between chemical structure and biological function is a major theme in the course. 3 hrs. lec, 1 hr. rec. |
|
| 09-105 |
Introduction to Modern Chemistry |
10 Units |
Fall and Spring |
| This course begins with a very brief survey of some fundamental principles of chemistry and a presentation of chemically interesting applications and sophisticated problems. These will form the basis for introducing various facets of the course that deal ultimately with the relationship between the structure of molecules and their chemical properties and behavior. The subject matter will include principles of atomic structure, chemical bonding, and molecular structures of organic and inorganic compounds including some transition metal complexes. Relevant examples will be drawn from such areas as environmental, materials, and biological chemistry. 3 hrs. lec, 2 hrs. rec. |
|
| 09-106 |
Modern Chemistry II |
10 Units |
Fall and Spring |
| The course provides an introduction to some basic concepts of chemical equilibria and thermodynamics. Topics may include gas phase equilibria, acid-base chemistry, solubilities, oxidation-reduction reactions, enthalpy, entropy, free energy, colligative properties and electrochemistry. Chemical kinetics is introduced to complement the study of thermodynamics. 3 hrs. lec., 2 hrs. rec. |
| Pre-req: 09-105 or 09-107 |
|
| 09-107 |
Honors Chemistry: Fundamental Concepts and Applications |
10 Units |
Fall |
| Honors Chemistry is an introductory course that teaches the foundations of Modern Chemistry and applies them to current scientific issues, such as Green Chemistry, Biotechnology and Materials Science. Topics include modern theories of bonding, organization of atoms, molecular interactions, biochemistry and transition metal chemistry. Enrollment is limited to first-year students, with priority given to those in MCS. 3 hrs. lec., 2 hrs. rec. |
|
| 09-201 |
Undergraduate Seminar I |
1 Units |
Fall |
| Issues and topics of importance to beginning chemistry majors are discussed in this course. It provides a general introduction to the facilities, faculty and programs of the Chemistry Department and introduces students to career and research opportunities in the field of chemistry. Students attend and evaluate seminars of fourth-year students. 1 hr. |
|
| 09-202 |
Undergraduate Seminar II |
1 Units |
Spring |
| Issues and topics focused on laboratory safety are discussed in this class. The topics are selected to supplement information covered in 09-221, Laboratory I. This course is intended to provide the necessary safety training for students wishing to undertake undergraduate research projects in the laboratory and is taught in collaboration with the Office of Environmental Health and Safety. Enrollment is limited to chemistry majors. 1 hr. |
|
| 09-204 |
Issues in Chemistry |
3 Units |
Spring |
| This course uses current issues in chemistry such as environmental and ethical topics as a vehicle for developing verbal and communication skills. 1 hr. lec. |
|
| 09-214 |
Physical Chemistry |
9 Units |
Spring |
| This is a one-semester course intended primarily for students in Biological Sciences, students in the B.A. degree program in Chemistry, and students from other departments interested in pursuing graduate studies in the health professions. The course focuses on thermodynamics and its application to chemical and biological systems. Emphasis is given towards attaining a good fundamental understanding of entropy and free energy. Topics include applications of thermodynamics to chemical and biochemical equilibria, electrochemistry, solutions, and chemical kinetics. 3 hrs. lec. |
| Pre-req: 09-106 and 21-118 and 33-111 and (09-105 or 09-107) |
|
| 09-217 |
Organic Chemistry I |
9 Units |
Fall |
| This course presents an overview of structure and bonding as it pertains to organic molecules. Selected topics include: introduction to functional group chemistry, stereochemistry, conformational analysis, reaction mechanisms and use of retrosynthetic analysis in the development of multistep syntheses. Methods for structure determination of organic compounds by modern spectroscopic techniques are introduced. 3 hrs. lec., 1 hr. rec. |
| Pre-req: (09-105 or 09-107) |
|
| 09-218 |
Organic Chemistry II |
9 Units |
Spring |
| This course further develops many of the concepts introduced in Organic Chemistry I, 09-217. Emphasis is placed on the utilization of reaction mechanisms for understanding the outcome of chemical transformations, and the employment of a wide variety of functional groups and reaction types in the synthesis of organic molecules. Also included in the course will be special topics selected from the following; polymers and advanced materials, biomolecules such as carbohydrates, proteins and nucleic acids, and drug design. 3 hrs. lec, 1 hr. rec. |
| Pre-req: 09-217 |
|
| 09-220 |
Supramolecular Organic Chemistry |
3 Units |
Spring |
| Supramolecular chemistry involves the use of noncovalent bonding interactions to assemble molecules into stable, well-defined structures. This course will provide students with an introduction to this exciting field of research. Students will be introduced to essential background concepts such as types of noncovalent bonding and strategies for the design of supramolecular assemblies. Readings from monographs and classroom lectures by the instructor will cover this material. Students will then begin to read about applications of supramolecular chemistry from the scientific literature, learning to compare articles, to evaluate the quality of the data and interpretations reached by the authors, to use the knowledge gained from these readings and discussions to predict the outcomes of related experiments, and to ultimately be able to design their own experiments to answer a relevant question. Meeting hours set by instructor, enrollment limited with priority given to sophomore chemistry majors. |
| Pre-req: 09-217 |
| Co-req: 09-218 |
|
| 09-221 |
Laboratory I: Introduction to Chemical Analysis |
12 Units |
Fall and Spring |
| This course is the first in a sequence of four laboratory courses on experimental aspects of chemistry. The experimental work emphasizes the techniques of quantitative chemical analysis. Included are projects dealing with a variety of instrumental and wet chemical techniques and have included spectroscopic methods, volumetric analysis including redox and acid-base titrations, gravimetric analysis, and high-pressure liquid chromatography as well as some preparative techniques used in organic and inorganic synthesis. The course is project-oriented with the experiments becoming more complex, requiring greater student input into the experimental design as the semester progresses. A mixture of individual and team experiments are conducted during the semester. In addition to techniques, safety, written, and oral communication skills, and effective teamwork are emphasized. 2 hrs. lec., 6 hrs. lab. |
| Pre-req: (09-106 or 09-206) |
|
| 09-222 |
Laboratory II: Organic Synthesis and Analysis |
12 Units |
Spring |
| This second course in the laboratory sequence introduces some important laboratory methods for synthesis and purification of organic compounds, as well as practical applications of spectroscopy and chromatography for characterization of organic compounds. Use of the chemical literature is included. 2 hrs. lec., 6 hrs. lab. |
| Pre-req: 09-217 and 09-221 |
| Co-req: 09-218 |
|
| 09-231 |
Mathematical Methods for Chemists |
9 Units |
Fall |
| This course covers mathematical techniques that are important in the chemical sciences. The techniques will be covered in the context of chemical phenomena, and combine topics from 3-dimensional calculus, differential equations, linear algebra and statistics. This course does not count towards the minor in chemistry. 3 hrs. lec. |
| Pre-req: 09-106 and 21-118 |
|
| 09-301 |
Undergraduate Seminar III |
1 Units |
Fall |
| Students attend one seminar per week on a chemistry related topic. A menu of choices is provided one week in advance. 1 hr. |
|
| 09-302 |
Undergraduate Seminar IV |
1 Units |
Spring |
| Students attend seminars presented by senior chemistry majors. Presentations are evaluated and students become familiar with special topics in chemistry. Some pointers on how to organize and present an effective seminar on a topic in chemistry are given. The course establishes what should be included in a good seminar. 1 hr. |
|
| 09-321 |
Laboratory III: Molecular Design and Synthesis |
12 Units |
Fall |
| This third course in the laboratory sequence is an advanced synthesis course covering a variety of synthetic methods including vacuum and inert atmosphere methods to prepare organic, inorganic, organometallic, and polymeric compounds. Methods may involve resolution procedures to prepare optically active compounds, separation of mixtures and isolation of products by use of column and thin-layer chromatography, sublimation and extraction techniques. Experiments on characterization and identification by chemical and spectroscopic methods form an important part of the course. Use of the chemical literature is included. 2 hrs. lec,. 6 hrs. lab. |
| Pre-req: 09-218 and 09-222 |
|
| 09-322 |
Laboratory IV: Molecular Spectroscopy and Dynamics |
12 Units |
Spring |
| This laboratory course is devoted to physical chemistry experiments, which involve the use of modern spectroscopic instrumentation to probe the optical and magnetic properties of molecules. The experiments include the use of high-resolution infrared, laser Raman, NMR, EPR, fluorescence, and UV-visible spectroscopies. Additional experiments demonstrate methods for measuring phase equilibria and enzyme-catalyzed reaction rate constants, and develop skills in error analysis, basic electronics, and vacuum techniques. 2 hrs. lec., 6 hrs. lab. |
| Pre-req: 09-221 and 09-344 |
| Co-req: 09-345 |
|
| 09-331 |
Modern Analytical Instrumentation |
9 Units |
Fall |
| This course will cover all aspects of analytical instrumentation and its application to problems in materials, environmental, and biological chemistry. Topics covered will include chromatographic separations, mass spectrometry, optical spectroscopies, electrochemistry, optical and force microscopies and potentially NMR. In addition, the course will emphasize how to select an analytical method appropriate to the problem at hand, how to optimize the signal to noise obtained by a measurement, and the quantitative analysis of experimental data. 3 hrs. lec. |
| Pre-req: 09-221 and 09-222 |
| Co-req: 09-344 |
|
| 09-344 |
Physical Chemistry (Quantum): Microscopic Principles of Physcial Chemistry |
9 Units |
Fall |
| The measurement and theoretical description of the properties of atoms and molecules are presented. The elementary principles of quantum chemistry are developed. The many types of spectroscopy used to study atoms and molecules are described. Methods of atomic structure determination are discussed. The structure and properties of solids are also presented. The basic results of statistical chemistry are outlined and a brief connection to thermodynamics is made. 3 hrs. lec., 1 hr. rec. |
| Pre-req: (09-105 or 09-107) and (21-259 or 09-231). |
|
| 09-345 |
Physical Chemistry (Thermo): Macroscopic Principles of Physical Chemistry |
9 Units |
Spring |
| The measurement and theoretical descriptions of the equilibrium properties of chemical systems are presented. Chemical thermodynamics is introduced at the upper division level. The phases of matter are discussed. The quantitative treatment of mixtures is developed. The detailed description of chemical equilibrium is elaborated. The measurement and theoretical description of the nonequilibrium properties of chemical systems are presented. Elementary transport properties are introduced. The principles of classical chemical kinetics are developed in great detail. 3 hrs. lec., 1 hr. rec. |
| Pre-req: 09-106 and (21-259 or 09-231). |
|
| 09-347 |
Advanced Physical Chemistry |
12 Units |
Fall |
| A course of study designed to provide the microscopic basis of concepts encountered in the field of chemical engineering. The properties of macroscopic materials are calculated in terms of the microscopic properties of atoms and molecules. Both classical and quantum approaches are employed. The thermodynamic properties are developed in terms of the chemical potentials of the constituent particles. The transport properties are calculated using molecular dynamics and Brownian dynamics. Classical chemical kinetics is fully developed and applied to complex reactions. Rate constants are calculated for simple reactions in gases and solutions. The course is limited to chemical engineering majors. 5 hrs. lec. |
| Pre-req: (06-151 or 06-221) and (06-155 or 06-262) and (09-105 or 09-107) |
|
| 09-348 |
Inorganic Chemistry |
10 Units |
Spring |
| The focus of this class is the understanding of the properties of elements and inorganic compounds. The electronic structure of the elements will be discussed as the basis for their organization in the Periodic Table and for their properties. The systematic chemistry of main group elements and of transition metals will be presented. The number of inorganic compounds is extremely large and their properties are extremely diverse. Therefore in this course, the presentation of physical and chemical properties of inorganic compounds will be based on observation of the trends in the respective properties and the relation between these trends and the place of the elements in the Periodic Table. The biological role of inorganic compounds present in the living matter will be illustrated in the part of the class dedicated to the study of bioinorganic chemistry. 3 hrs. lec., 1 hr. rec. |
| Pre-req: 09-106 |
|
| 09-401 |
Undergraduate Seminar V |
1 Units |
Fall |
| Offered as a 7 week mini-course, students review the skills necessary for giving an effective oral technical presentation. The poster as a tool for communicating technical information is discussed. The course concludes with a poster session by participants. |
|
| 09-402 |
Undergraduate Seminar VI |
3 Units |
Fall and Spring |
| Students enrolled in this course present a 20 - 30 minute oral report on a current topic in chemistry. This may be from the student's research work or a special chemistry topic of general interest. Presentations or papers prepared for other courses are not acceptable. Thoroughness in the use of the chemical literature is emphasized. The use of presentation aids such as PowerPoint is encouraged. Other students in the class submit written evaluations of the presentation. A seminar presentation is required of all chemistry majors. No exceptions possible. 1 hr. |
|
| 09-441 |
Nuclear and Radiochemistry |
9 Units |
Intermittent |
| This course is designed for upper level science and engineering students, and provides an introduction to the fundamentals and applications of nuclear phenomena. Among the topics discussed are the systematics of stable and unstable nuclei, nature and energetics of radioactivity, detection and measurement of nuclear radiation, tracer techniques in chemical applications, nuclear processes as chemical probes, and nuclear energy. (Graduate Course: 12, 09-732) |
| Pre-req: 09-345 |
|
| 09-445 |
Undergraduate Research |
3 to 18 Units |
Fall and Spring |
| Properly qualified students may undertake research projects under the direction of members of the faculty, normally 6 to 12 hrs/week. A written, detailed report describing the project and results is required. Course may be taken only with the consent of a faculty research advisor in chemistry or on occasion in another department provided that the project is chemical in nature and with permission of the Director of Undergraduate Studies. The number of taken generally corresponds to the actual number of hours the student actually spends in the lab doing research during the week. Maximum number of taken per semester is 18. |
|
| 09-455 |
Honors Thesis |
6 to 15 Units |
Fall and Spring |
| Students enrolled in the departmental Honors program are required to enroll in this course to complete the honors degree requirements. A thesis written in an acceptable style describing an original research project, and a successful oral defense of the thesis topic before an Honors Committee are required. Limited to students accepted into the honors program. (B.S. Honors candidates normally enroll for 6; B.S./M.S. candidates enroll for 15.) |
|
| 09-502 |
Organic Polymer Chemistry |
9 Units |
Spring |
| A study of the synthesis and reactions of high polymers. Emphasis is on practical polymer preparation and on the fundamental kinetics and mechanisms of polymerization reactions. Topics include: relationship of synthesis and structure, step-growth polymerization, chain-growth polymerization via radical, ionic and coordination intermediates, copolymerization, discussions of specialty polymers and reactions of polymers. (Graduate Course: 12, 09-741) |
| Pre-req: 09-218 |
|
| 09-504 |
Chemical Kinetics |
9 Units |
Intermittent |
| Rate laws. Analysis of linear chemical networks by Leplace transform and matrix formalism. Transient and steady-state methods. Stability of chemical systems. Theories of reaction rates. Molecular energetics. Application to reactions in solution, electrolytes, electron and proton transfer reactions, heterogeneous systems. (Graduate Course: 09-704, 12) |
|
| 09-509 |
Physical Chemistry of Macromolecules |
9 Units |
Fall |
| This course develops fundamental principles of polymer science. Emphasis is placed on physio-chemical concepts associated with the macromolecular nature of polymeric materials. Engineering aspects of the physical, mechanical and chemical properties of these materials are discussed in relation to chain microstructure. Topics include an introduction to polymer science and a general discussion of commercially important polymers; molecular weight; condensation and addition synthesis mechanisms with emphasis on molecular weight distribution; solution thermodynamics and molecular conformation; rubber elasticity; and the rheological and mechanical properties of polymeric systems. (This course is also listed as 06-609.) 3 hrs. lec. |
| Pre-req: 09-345 |
|
| 09-510 |
Introduction to Green Chemistry |
9 Units |
Spring |
| This course covers the most significant emerging field in modern chemistry, namely, Green chemistry, the field, which focuses upon the reinvention of chemistry such that pollution can be avoided. Sustainabilty ethics will be introduced and discussed. The "principles of green chemistry" will be presented and analyzed. The chemical nature and action of certain pollutants of the atmosphere, land, and water, will be highlighted along with prospects for their minimization, and approaches for their eradication. Particular attention will be paid to sources and potential replacements of persistent bioaccumulative pollutants. A historical and technical analysis of the chlorine industry and pollution emanating from this industrial sector will be covered in some detail. The recently discovered mechanism of toxicity called "endocrine disruption" will be presented in the context of this industry. The chemical process by which white paper is made will be treated in detail emphasizing the environmental effluent problems and the steps that industry has taken to reduce these problems. A new technology with potential to further significantly reduce toxic effluents in this and other industrial sectors will be described and students will examine the use of the technology in a laboratory setting: this technology has been invented at Carnegie Mellon. Themes woven throughout the course include emerging concepts for guiding green chemistry, environmental toxicology, conventional versus biorational pesticides, the development of green oxidants, and an identification of toxins, especially persistent toxins, where elimination will require new green chemistry. A significant effort has been made by the instructor to produce a course suitable for an interdisciplinary audience
and recent classes have come from diverse backgrounds throughout the university. (Graduate Course: 09-710, 12 units) 3 hrs. lec. |
| Pre-req: 09-218 and 09-348 |
|
| 09-511 |
Solid State and Material Chemistry |
9 Units |
Intermittent |
| The course will interface general principles in solid-state physics and chemistry as applied to novel organic and inorganic materials. The general focus of the course will be on electronic materials. Specific topics to be covered include: solid state structures, the free electron model, energy bands (Bloch theory, tight binding model, etc.) and electrical conductivity. Techniques for defining both the electronic and physical structures and properties of solids will be discussed throughout the course. Magnetic and optical properties of some organic and inorganic materials will be covered. (Graduate Course: 12, 09-811) |
| Pre-req: 09-218 and 09-345 |
|
| 09-517 |
Organotransition Metal Chemistry |
9 Units |
Fall |
| The first half of this course focuses on the fundamentals of structure and bonding in organotransition metal complexes and how the results can be used to explain, and predict, chemical reactivity. The latter half of the course covers applications, and more specifically, homogeneous catalysts for industrial processes and organic synthesis. (Graduate Course: 12, 09-717) |
|
| 09-518 |
Bioorganic Chemistry |
9 Units |
Fall |
| This course will introduce students to new developments in chemistry and biology, with emphasis on synthetic and functional aspects of nucleic acids and proteins, and their applications. Later in the course, students will get to explore some of the ongoing research in functional genomics. Students will be required to keep abreast of the current literature, and homework will be assigned on a regular basis. The homework assignments will require data interpretation and experimental design. (Graduate Course: 12, 09-718) 3 hrs. lec. |
| Pre-req: 09-217 and 09-218 |
|
| 09-520 |
Special Topics in Atmospheric Chemistry |
9 Units |
Fall |
| This course will explore global atmospheric chemistry through a series of case studies: Stratospheric Ozone, Global Methane and OH, and Urban and Regional Ozone. Each case will begin with a description of the chemistry and atmospheric physics fundamental to the particular problem. Students will formulate testable mathematical models incorporating that chemistry and physics, turning then to existing atmospheric data sets to test current understanding. The emphasis of this course is to develop an understanding of how to pose a testable hypotheses in a complex chemical environment such as the atmosphere, validate or refute those hypotheses, and then by extension predict how the system will respond to perturbations. A particular objective is to explore how to extend this methodology from the stratosphere and background troposphere (the first two cases), where it has been applied with success, to the much more complicated problem of urban and regional air quality. (This course is also listed as 06-620.) |
| Pre-req: 21-260 |
| Co-req: (09-347 or 09-344) |
|
| 09-521 |
Bioinorganic Chemistry |
9 Units |
Intermittent |
| The course addresses the basis for the selection and regulation of metal atoms and ligand systems and their interactions with their corresponding protein environments. The chemistry of catalytic processes in metalloenzymes, and atom transfer and electron transport in metalloproteins will be reviewed. The array of physical methods required for study will be introduced, with application toward the determination of electronic and molecule structure and enzymatic mechanisms. (Graduate Course: 09-721 12 units) |
| Pre-req: 09-344 and 09-348 |
|
| 09-522 |
Oxidation and Inorganic Chemistry |
9 Units |
Intermittent |
| The roles of metal complexes in oxidation processes (inorganic, organic, biological) will be presented. Special attention is given to processes involving the activation of molecular oxygen and hydrogen peroxide from a mechanistic viewpoint. The electronic structures of metal complexes of dioxygen and its reduced species superoxide, peroxide, and oxide are reviewed, as are the relationships between electronic structure and oxidation reactivity. (Graduate Course: 12, 09-722) |
| Pre-req: 09-348 |
|
| 09-541 |
Spectroscopy |
9 Units |
Spring |
| This course emphasizes the use of modern optical methods in the study of molecular properties and reactivity. Basic topics such as the use of group theory in the analysis of vibrational, rotational and electronic spectra are covered in detail. In addition, recently developed techniques such as time-resolved and nonlinear spectroscopies are discussed as are applications of optical methods to problems in chemistry, biology and materials science. (Graduate Course: 12, 09-841) |
| Pre-req: 09-344 and 09-345 |
|
| 09-545 |
Polymer Rheology |
9 Units |
Intermittent |
| A survey of the mechanical properties of polymeric materials in their many forms: melt, rubber, glass, crystalline, solution, mixtures, and composites with other materials. The dependence on structure of viscosity, viscoelasticity, and plasticity failure. The role of rheological properties in characterization, testing, fabrication, and use of polymeric materials. (Graduate Course: 12, 09-745) |
| Pre-req: (09-344 or 09-347) and (09-509 or 06-609). |
|
| 09-560 |
Computational Chemistry |
12 Units |
Fall |
| Computer modeling is playing an increasingly important role in chemical research. This course provides an overview of computational chemistry techniques including molecular mechanics, molecular dynamics and both semi-empirical and ab initio electronic structure theory. Sufficient theoretical background is provided for students to understand the uses and limitations of each technique. An integral part of the course is hands on experience with state-of-the-art computational chemistry tools running on graphics workstations. 4 hrs. lec. |
| Pre-req: (15-111 or 15-200) and 09-344 and 09-345 |
|
| 09-701 |
Quantum Chemistry I |
12 Units |
Fall |
| Introduction to quantum mechanics. The main topics to be covered will include wave packets, interference, the uncertainty principle, Ehrenfest's theorem, the Schroedinger equation and its solution for finite and infinite square wells and barriers, the harmonic oscillator, the rigid rotor, the hydrogen atom and time-independent perturbations. |
| Pre-req: permission of instructor |
|
| 09-702 |
Statistical Mechanics and Dynamics |
12 Units |
Intermittent |
| Application of statistical mechanics to chemical systems. Calculation of thermodynamic functions, phase transitions and chemical equilibrium. Calculation of transport properties of gases and liquids. Elementary theory of chemical kinetics. |
| Pre-req: permission of instructor |
|
| 09-711 |
Physical Organic Chemistry |
12 Units |
Intermittent |
| The study of the structure and reactivity of organic molecules from a physical and theoretical standpoint. Introduction to molecular orbital theory and the study of mechanisms in pericyclic, electron-transfer, photochemical and heterolytic reactions by the use of physical methods such as kinetics, isotope effects, substituent effects and spectroscopic methods. |
| Pre-req: permission of instructor |
|
| 09-712 |
Synthetic Organic Chemistry |
12 Units |
Intermittent |
| General synthetic strategies are discussed with a focus on C-C bond formation, functional group transformations, unnatural products and mechanisms. |
| Pre-req: permission of instructor |
|
| 09-720 |
Physical Inorganic Chemistry |
12 Units |
Intermittent |
| This course develops principles of magnetochemistry and inorganic spectroscopy. Electronic absorption, magnetic circular dichroism, resonance raman, NMR, EPR, Mossbauer, magnetization and x-ray methods will be introduced with application toward the determination of electronic structures of transition metal complexes. |
| Pre-req: permission of instructor |
|
| 09-746 |
Linear Viscoelasticity |
12 Units |
Intermittent |
| The mathematical model for linear viscoelasticity is developed and compared with the behavior observed for polymeric materials. Emphasis is on the interpretation of experimental results in terms of fundamental material properties and discussion of the latter in terms of molecular concepts for a variety of amorphous and crystalline polymers. |
| Pre-req: permission of instructor |
|
| Course | Title | Units | Semester |
|
| 12-090 |
Technology and the Environment |
9 Units |
Spring |
| Technical elective for undergraduate, non-engineering majors. Overview of major environmental issues and concerns associated with modern technology. Topics in the course include automobiles and associated air emissions and fuel consumption, information technology and electricity usage, electricity generation and alternative sources to reduce air emissions and wastes, CFCs and their influence on the ozone layer, and various issues related to land use patterns such as agriculture and infrastructure. Methods for using technology to improve environmental conditions also discussed. Within this framework the course aims to build fundamental problem solving skills, basic familiarity with engineering calculations, and writing proficiency. The overall purpose is to instill an appreciation of the complexity of issues and viewpoints surrounding technology development and associated environmental impacts. |
| Pre-req: permission of instructor |
|
| 12-100 |
Introduction to Civil and Environmental Engineering |
12 Units |
Fall and Spring |
| Presentation of selected topics in the discipline with an emphasis on fundamentals. The course includes treatment of topics in mechanics and provides an exposure to environmental engineering. Problem-solving exercises within the course apply these concepts to integrate the steps of analysis, synthesis, and evaluation through individual and group projects that require attention to a broad range of issues. The course also exposes the students to issues related to engineering practice such as scheduling, evaluating risk, and making ethical decisions. In addition to regular lectures and project exercises, the course includes guest speakers, field trips, and class demonstrations. 3 hrs., rec., 1 hr.lab. |
| Co-req: 21-115, 21-116, 33-106 |
|
| 12-235 |
Statics |
9 Units |
Spring |
| Introduction to vector mechanics; equivalent systems of forces; equilibrium of rigid bodies; free body diagram; distributed forces, hydrostatic forces, effective forces, centroids; applications to simple statically determinate trusses, beams, frames, cables and other physical systems; friction. 3 hrs. rec. |
| Co-req: 12-100, 21-117, 21-118, 33-106 |
|
| 12-251 |
Introduction to Environmental Engineering |
9 Units |
Fall |
| Provides a scientific and engineering basis for understanding environmental issues and problems. Introduces material and energy balances for tracking substances in the atmosphere, surface and ground waters, and soil systems. Pertinent environmental laws are described, simple quantitative engineering models are developed, and qualitative descriptions of environmental engineering control technologies are presented. 3hrs. rec. |
| Pre-req: 06-101 or 12-100 |
|
| 12-252 |
Introduction Environment Engineering Lab |
3 Units |
Fall |
| (Required for CEE students, not for others) Laboratory and field experiments that illustrate the basic principles of environmental engineering. 1 hr. lab. |
| Co-req: 12-251 |
|
| 12-271 |
Introduction to Computer Applications in Civil & Environmental Engineering |
9 Units |
Fall |
| Introduction to the use of computer-based applications in civil engineering, using generic tools such as spread-sheets, equation solvers and computer graphics. Discussion of the role of computer-based methods in civil engineering practice. 3 hrs. rec. |
| Pre-req: 21-115 and 21-116 and 33-106 |
|
| 12-301 |
CEE Projects |
12 Units |
Fall |
| Basic elements of civil and environmental engineering projects, from project conception through design, to implementation and operation. Project components are explored through formal instruction combined with analysis of actual engineering projects and student team activities. The course is intended to develop skills and understanding related to the application of engineering and science principles, approximations, empiricism, and experience to engineering projects; basic theory and practice of design; the importance and challenge of team efforts and effective communication; and the utility of measurements, modeling, visualization, quality control, and engineering graphics. 4 hrs. rec. |
| Pre-req: 12-235 and 12-251 and 12-271 |
|
| 12-331 |
Solid Mechanics |
9 Units |
Fall |
| Analysis of deformable bodies incorporating concepts of stress, strain, mechanical properties of materials, and geometric compatibility. Response under axial loads, torsion, bending, transverse shear, and combined loadings. Stress and strain transformations and Mohr's circles, deflections of beams and shafts, buckling of columns. |
| Pre-req: 12-235 |
| Co-req: 21-259 |
|
| 12-332 |
Solid Mechanics Lab |
3 Units |
Fall |
| Analysis of stress-strain relationships, torsion of solid shafts, deformation due to bending, deformations in three dimensions, Mohr?s circle representation of stress and strain, buckling of slender columns. Laboratory experiments and reports associated with theoretical concepts. 1 hr. lab. |
| Pre-req: 12-235 |
| Co-req: 12-331 |
|
| 12-335 |
Soil Mechanics |
9 Units |
Spring |
| Sampling, testing and identification of soils. Physical, chemical and hydraulic characteristics. Stress-strain-strength relationships for soils. Permeability, seepage, consolidation, and shear strength, with applications to deformation and stability problems, including earth dams, foundations, retaining walls, slopes and landfills. 3 hrs. rec. |
| Pre-req: 12-331 |
| Co-req: 12-355 |
|
| 12-336 |
Soil Mechanics and Materials Laboratory |
3 Units |
Spring |
| Examination of material properties and behavior of soils, concrete, steel, polymers, and |